Clinical Trial at Duke Shows Vaccine Fights Brain Cancer
Vaccines are the front line of defense against viral disease but they have also joined the fight against the most common and deadly type of brain cancer.
Posted — UpdatedDuke researchers are using a vaccine to hopefully prevent recurrence of the most common and deadly type of brain tumors. As opposed to most other cancer treatments, the vaccine does not have negative side effects. So far, the trial has shown promising results.
In December of 2005, Pam Shelley had a car accident on her way to work near her Goose Creek, S.C., home.
"I don't know if I had a seizure or just blacked out, but I wrecked into a ditch," said Shelley.
It was the first symptom for what turned out to be a brain tumor. Without effective treatment her doctors said she might have only a year and a half to live.
Dr. Sampson said it was the most common and aggressive type of brain cancer, a glioblastoma multiforme (GBM). Typically, surgery is unable to remove all (GBM) cancer.
Beyond surgery, radiation and chemotherapy, a Duke clinical trail offered Shelley a new, non-toxic option.
Dr. Sampson said after three to six months, Shelley's tumor was shrinking.
Dr. Sampson.
Shelley will come back to Duke for monthly boosters and brain scans to make sure the cancer has not returned.
Dr. Sampson said that it is not known how often the booster vaccines are really needed, but monthly is the safest bet.
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